产品货号：
Z12638
中文名称：
CD18/ITGB2抗体
英文名称：
Anti-CD18/ITGB2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD18/ITGB2 Antibody |
| 指标别名 | CD18;Integrin beta 2;ITGB2;LAD;LCAMB;LFA 1;MAC 1;MF17;MFI7 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | ITGB2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human CD18(24-58aa,ECTKFKVSSCRECIESGPGCTWCQKLNFTGPGDPD),different from the related mouse sequence by five amino acids. |
| 实际分子量 | 90～100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The beta-2 integrin chain gene is designated ITGB2 and the leukocyte antigen has been designated CD18.The 3 alpha integrin chains associated individually with the beta-2 chain as a heterodimer have gene designations of ITGAL,ITGAM,and ITGAX,and leukocyte antigen designations of CD11A,CD11B,and CD11C,respectively.The expression of CD18 was increased in lymphoblastoid cells from persons with Down syndrome,consistent with the location of the gene on chromosome 21.The ITGB2 gene spans approximately 40kb and contains 16 exons and all exon/intron boundaries conform to the GT/AG splicing consensus.Furthermore,ITGB2 was constitutively clustered.Although it was expressed on the cell surface at normal levels and was capable of function following extracellular stimulation,it could not be activated via the “inside-out” signaling pathways. |
| Uniprot ID | P05107 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | integrin,beta 2(complement component 3 receptor 3 and 4 subunit) |
| 蛋白名全称 | Integrin beta-2 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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